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Christophe Pannecouque Selected Research

Human immunodeficiency virus 1 reverse transcriptase

8/2022Chemical space exploration around indolylarylsulfone scaffold led to a novel class of highly active HIV-1 NNRTIs with spiro structural features.
2/2008Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.
9/2005Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors.

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Christophe Pannecouque Research Topics

Disease

14Infections
04/2021 - 07/2002
11Acquired Immunodeficiency Syndrome (AIDS)
12/2021 - 04/2006
8HIV Infections (HIV Infection)
01/2018 - 09/2005
5Human Influenza (Influenza)
03/2020 - 12/2003
4Neoplasms (Cancer)
10/2016 - 01/2002
3Virus Diseases (Viral Diseases)
04/2021 - 08/2012
2autosomal dominant Spastic paraplegia 6
08/2022 - 03/2021
2Dengue (Dengue Fever)
01/2021 - 01/2020
2Zika Virus Infection
01/2021 - 01/2020
1Liver Diseases (Liver Disease)
04/2021
1Drug-Related Side Effects and Adverse Reactions
02/2020
1Prostatic Neoplasms (Prostate Cancer)
01/2018
1Extensively Drug-Resistant Tuberculosis
01/2016
1AIDS-Related Lymphoma (Lymphoma, AIDS Related)
09/2015
1Hepatocellular Carcinoma (Hepatoma)
01/2013
1Wounds and Injuries (Trauma)
06/2010
1Furunculosis (Boils)
06/2010
1Noncommunicable Diseases
06/2010
1Carbuncle
06/2010
1Vaccinia
06/2009
1Vesicular Stomatitis
06/2009
1Melanoma (Melanoma, Malignant)
05/2006
1Leukemia
05/2006
1Synucleinopathies
03/2006
1Necrosis
11/2005

Drug/Important Bio-Agent (IBA)

13Antiviral Agents (Antivirals)IBA
04/2021 - 03/2002
10Pharmaceutical PreparationsIBA
03/2021 - 09/2012
9NucleosidesIBA
06/2020 - 01/2002
5Reverse Transcriptase InhibitorsIBA
06/2020 - 04/2006
3Human immunodeficiency virus 1 reverse transcriptaseIBA
08/2022 - 09/2005
2pyrimidineIBA
03/2020 - 06/2015
2Amantadine (Aman)FDA LinkGeneric
10/2015 - 06/2012
2Ribavirin (Virazole)FDA LinkGeneric
10/2015 - 06/2012
2RimantadineFDA LinkGeneric
10/2015 - 06/2012
1CarbonIBA
03/2021
1Indole AlkaloidsIBA
01/2021
13- (5- nitrofuryl)- 7- (5- nitrofurfurylidene)- 3,3a,4,5,6,7- hexahydro- 2H- indazoleIBA
05/2020
1Ribonuclease H (RNase H)IBA
03/2020
1Carboxylic AcidsIBA
01/2020
1Tryptophan (L-Tryptophan)FDA Link
01/2020
1Glycoproteins (Glycoprotein)IBA
01/2020
1AndrogensIBA
01/2018
1compound 18IBA
10/2016
1AGRO 100IBA
04/2016
1ThioureaIBA
01/2016
1UracilIBA
01/2016
11,3,4-thiadiazoleIBA
01/2016
1Amino AcidsFDA Link
12/2015
1BenzenesulfonamidesIBA
12/2015
1PurinesIBA
10/2015
1piperidineIBA
10/2015
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
06/2015
1BRACO-19IBA
12/2014
1Single-Domain AntibodiesIBA
12/2014
12- methyl- 3- phenyl- 2H- (1,2,4)thiadiazol- 5- ylideneamineIBA
11/2012
1Human immunodeficiency virus 1 p16 proteaseIBA
09/2012
1HIV ProteaseIBA
09/2012
1ThiazolesIBA
06/2012
1oseltamivir carboxylateIBA
06/2012
1acetamideIBA
06/2012
1Ointments (Pastes)IBA
06/2010
1PowdersIBA
06/2010
1Alcian BlueIBA
11/2009
1CarbohydratesIBA
11/2009
1phthalocyanineIBA
11/2009
1ProdrugsIBA
06/2009
1EstersIBA
06/2009
1DipeptidesIBA
06/2009
1Acyclovir (Aciclovir)FDA LinkGeneric
06/2009
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
02/2008
1Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
02/2008
1HIV Reverse TranscriptaseIBA
10/2007
1QuinolonesIBA
04/2007
1ZincIBA
10/2006
1Cytostatic AgentsIBA
05/2006
1IonsIBA
03/2006
1alpha-SynucleinIBA
03/2006
1MetalsIBA
03/2006
1phorbolIBA
11/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2005
1RNA (Ribonucleic Acid)IBA
05/2005
1Green Fluorescent ProteinsIBA
05/2005
1L 708906IBA
10/2002
1EnzymesIBA
07/2002
1Complementary DNA (cDNA)IBA
07/2002
1HIV IntegraseIBA
07/2002
1ThiosemicarbazonesIBA
03/2002

Therapy/Procedure

12Therapeutics
12/2021 - 07/2002
4Highly Active Antiretroviral Therapy (HAART)
01/2018 - 10/2007
1Oral Administration
09/2015